Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282892 | 0.94 | ELANE (0.75) | ELANECTRC | |
| SCHEMBL7276591 | 0.90 | ELANE (0.80) | ELANECTRC | |
| SCHEMBL7284464 | 0.89 | ELANE (0.78) | ELANECTRC | |
| SCHEMBL7282876 | 0.87 | ELANE (0.79) | ELANECTRC | |
| SCHEMBL7283371 | 0.87 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL6556283 | 0.83 | ELANE (0.70) | ELANECTRC | |
| SCHEMBL7282953 | 0.83 | ELANE (0.73) | ELANECTRC | |
| SCHEMBL7274260 | 0.81 | ELANE (0.67) | ELANECTRC | |
| SCHEMBL7273639 | 0.81 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL7276671 | 0.81 | ELANE (1.00) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086076-A1 | SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE | Vertex Pharmaceuticals Incorporated (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065870-A2 | SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |