Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 6/20 | 0.57 |
| ▸ | FABP7 | O15540 | 4/20 | 0.57 |
| ▸ | FABP3 | P05413 | 3/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19355194 | 0.97 | FABP5 (0.61) | FABP5FABP7FABP3SLC18A3SMN1; SMN2 | |
| SCHEMBL15570630 | 0.97 | FABP5 (0.61) | FABP5FABP7FABP3SLC18A3SMN1; SMN2 | |
| SCHEMBL4193263 | 0.97 | FABP5 (0.61) | FABP5FABP7FABP3SLC18A3SMN1; SMN2 | |
| SCHEMBL19355090 | 0.97 | FABP5 (0.61) | FABP5FABP7FABP3SLC18A3SMN1; SMN2 | |
| SCHEMBL19355089 | 0.97 | FABP5 (0.61) | FABP5FABP7FABP3SLC18A3SMN1; SMN2 | |
| SCHEMBL4193266 | 0.97 | FABP5 (0.61) | FABP5FABP7FABP3SLC18A3SMN1; SMN2 | |
| SCHEMBL8847691 | 0.84 | FABP5 (0.62) | FABP5FABP7FABP3SLC18A3SMN1; SMN2 | |
| SCHEMBL4607042 | 0.84 | GRIA4 (0.43) | FABP5FABP7FABP3SLC18A3SLC6A2 | |
| SCHEMBL25369789 | 0.83 | FABP5 (0.64) | FABP5FABP7FABP3SLC18A3SMN1; SMN2 | |
| SCHEMBL21825849 | 0.83 | FABP5 (0.64) | FABP5FABP7FABP3SLC18A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386675-B1 | Xanthine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5068236-A | Diuretics, renal protective agents and hypotensives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0386675-A2 | Xanthine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |