Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524899 | 0.98 | TSHR (0.40) | TSHRGAA | |
| SCHEMBL28891621 | 0.78 | GAA (0.39) | TSHRGAAALDH1A1 | |
| SCHEMBL4445265 | 0.76 | MGAM (0.43) | TSHRGAAALDH1A1 | |
| SCHEMBL483310 | 0.74 | MGAM (0.41) | GAA | |
| SCHEMBL10897591 | 0.73 | TSHR (0.42) | TSHRGAACYP2C19 | |
| SCHEMBL6939745 | 0.73 | GAA (0.46) | TSHRGAAALDH1A1CYP2C19 | |
| SCHEMBL14549832 | 0.71 | — | — | |
| SCHEMBL1107368 | 0.70 | GAA (0.44) | TSHRGAAALDH1A1CYP2C19 | |
| SCHEMBL20361867 | 0.70 | GAA (0.44) | TSHRGAAALDH1A1CYP2C19 | |
| SCHEMBL784657 | 0.70 | GAA (0.44) | TSHRGAAALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4726491-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| EP-1644384-A2 | PROCESS AND INTERMEDIATES FOR SYNTHESIS ENTECAVIR | Bristol-Myers Squibb Company (US) | 2006-04-12 | — | — | EP | claimed |
| JP-2006509800-A | — | — | 2006-03-23 | — | — | JP | claimed |
| WO-2004052310-A2 | PROCESS AND INTERMEDIATES FOR SYNTHESIS ENTECAVIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | claimed |