Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266484 | 0.90 | CACNA1B (0.73) | CACNA1B | |
| SCHEMBL5855180 | 0.89 | CACNA1B (0.73) | CACNA1B | |
| SCHEMBL5856752 | 0.88 | CACNA1B (0.71) | CACNA1B | |
| SCHEMBL5856296 | 0.87 | CACNA1B (0.71) | CACNA1B | |
| SCHEMBL5855026 | 0.87 | CACNA1B (0.70) | CACNA1B | |
| SCHEMBL7267420 | 0.87 | CACNA1B (0.68) | CACNA1B | |
| SCHEMBL7524274 | 0.87 | CACNA1B (0.79) | CACNA1B | |
| SCHEMBL7266791 | 0.86 | CACNA1C (0.65) | CACNA1BMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7530458 | 0.86 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL5855287 | 0.86 | CACNA1B (0.72) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |