Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL27291958 | 1.00 | ELANE (0.71) | ELANE | |
| SCHEMBL7286035 | 0.88 | ELANE (0.75) | ELANE | |
| SCHEMBL27316255 | 0.88 | ELANE (0.75) | ELANE | |
| Trifluoromethanesulfonic Acid SCHEMBL9746471 | 0.81 | ELANE (0.50) | ELANE | |
| SCHEMBL27293502 | 0.79 | ELANE (0.77) | ELANE | |
| SCHEMBL7276954 | 0.79 | ELANE (0.77) | ELANE | |
| SCHEMBL7279268 | 0.79 | ELANE (1.00) | ELANE | |
| SCHEMBL7289203 | 0.79 | ELANE (0.81) | ELANE | |
| SCHEMBL7287017 | 0.73 | ELANE (1.00) | ELANE | |
| SCHEMBL9744941 | 0.73 | ELANE (0.81) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291234-B1 | Peptidic human leukocyte elastase (HLE) inhibitors | ZENECA INC (US) | 1994-03-23 | — | — | EP | disclosed |
| US-5164371-A | HETEROCYCLIC KETONES | ICI AMERICAS INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0291234-A2 | Peptidic human leukocyte elastase (HLE) inhibitors | ZENECA INC. (US) | 1988-11-17 | — | — | EP | disclosed |