Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.42 |
| ▸ | HMGCR | P04035 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211279 | 0.98 | TSHR (0.58) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL5855801 | 0.93 | TSHR (0.55) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL7279691 | 0.91 | TSHR (0.61) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL8211719 | 0.88 | TSHR (0.73) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL8213043 | 0.88 | TSHR (0.65) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL28701951 | 0.88 | TSHR (0.65) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL5872279 | 0.88 | TSHR (0.73) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL6576796 | 0.88 | TSHR (0.73) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL10804043 | 0.86 | TSHR (0.61) | TSHRALDH1A1PTPN7HMGCRRECQL | |
| SCHEMBL7284670 | 0.83 | TSHR (0.62) | TSHRALDH1A1PTPN7HMGCRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039674-A | Calcium antagonistics | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| US-4782160-A | CALCIUM RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0276552-A1 | 1,4-dihydropyridine derivatives and their production | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |