Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.58 |
| ▸ | PDE4A | P27815 | 14/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276559 | 1.00 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7270529 | 0.87 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7289526 | 0.87 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7271066 | 0.87 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7271064 | 0.87 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7270534 | 0.87 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7278849 | 0.86 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7278844 | 0.86 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7289537 | 0.86 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7277081 | 0.86 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007501-A1 | ENZYMATIC RESOLUTION OF ENDO-BICYCLO[2.2.1]HEPTAN-2-OL AND DERIVED PHARMACEUTICAL AGENTS | PFIZER INC. (US) | 1991-05-30 | — | — | WO | claimed |
| EP-0428302-A2 | Enzymatic resolution of endo-bicycle(2.2.1)-heptan-2-ol and derived pharmaceutical agents | PFIZER INC. (US) | 1991-05-22 | — | — | EP | claimed |