Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395129 | 0.81 | CTNNB1 (0.54) | CTNNB1TDP1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL1193153 | 0.81 | CTNNB1 (0.50) | CTNNB1TDP1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL27456521 | 0.80 | CYP1A2 (0.50) | CTNNB1TDP1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL10390355 | 0.80 | CTNNB1 (0.47) | CTNNB1TDP1CYP1A2ACP3HPGD | |
| Naphthalen-1-Yl-Methanol SCHEMBL28403 | 0.78 | CYP1A2 (0.60) | CTNNB1TDP1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7394253 | 0.78 | CTNNB1 (0.54) | CTNNB1TDP1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7287691 | 0.77 | CTNNB1 (0.58) | CTNNB1TDP1CYP1A2ACP3MEN1 | |
| SCHEMBL7268294 | 0.77 | CTNNB1 (0.58) | CTNNB1TDP1CYP1A2ACP3MEN1 | |
| SCHEMBL7267021 | 0.77 | CTNNB1 (0.58) | CTNNB1TDP1CYP1A2ACP3MEN1 | |
| SCHEMBL10778471 | 0.77 | ACP3 (0.62) | CTNNB1TDP1CYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507278-A2 | Immobilised biocatalyser, its preparation and use for ester synthesis in a column reactor | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-07 | — | — | EP | claimed |
| EP-0727494-B1 | Method for the enzymatic acylation of alcohols with alkoxyvinylacetates through transesterification | HOECHST AG (DE) | 1998-09-30 | — | — | EP | disclosed |
| US-5756321-A | Process for enzymatic acylation of alcohols with alkoxyvinyl acetates by transesterification | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0727494-A1 | Method for the enzymatic acylation of alcohols with alkoxyvinylacetates through transesterification | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0377139-B1 | N-substituted acylamino acid compounds, process for their production and their use | BANYU PHARMA CO LTD (JP) | 1995-07-12 | — | — | EP | disclosed |
| US-5424309-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0507278-A2 | Immobilised biocatalyser, its preparation and use for ester synthesis in a column reactor | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-07 | — | — | EP | disclosed |
| EP-0377139-A1 | N-substituted acylamino acid compounds, process for their production and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1990-07-11 | — | — | EP | disclosed |
| EP-0173041-B1 | 2-SUBSTITUTED-1,3-PROPYLIDENEDIPHOSPHONATE DERIVATIVES, THE PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1988-11-30 | — | — | EP | disclosed |
| US-4696920-A | CARDIOVASCULAR DISORDERS | SYMPHAR S.A. (CH) | 1987-09-29 | — | — | US | disclosed |
| EP-0173041-A1 | 2-Substituted-1,3-propylidenediphosphonate derivatives, the process for their preparation and pharmaceutical compositions containing them | SYMPHAR S.A. (CH) | 1986-03-05 | — | — | EP | disclosed |