Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277165 | 1.00 | STING1 (0.52) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7277158 | 1.00 | STING1 (0.52) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12013385 | 0.82 | STING1 (0.51) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3060776 | 0.82 | STING1 (0.51) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL4457220 | 0.81 | STING1 (0.50) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL29424281 | 0.81 | STING1 (0.50) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7277487 | 0.80 | STING1 (0.52) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7267988 | 0.80 | STING1 (0.52) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9204578 | 0.79 | STING1 (0.63) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1589579 | 0.76 | STING1 (0.68) | STING1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352832-B1 | COMPOUNDS WITH BRONCHODILATOR ACTIVITY | AKZO N.V. (NL) | 1992-05-06 | — | — | EP | disclosed |
| US-5026724-A | Benzothiophene derivatives | AKZO N.V. (NL) | 1991-06-25 | — | — | US | disclosed |
| EP-0352832-A1 | Compounds with bronchodilator activity | AKZO N.V. (NL) | 1990-01-31 | — | — | EP | disclosed |