⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156727 | 0.72 | — | — | |
| SCHEMBL11389546 | 0.72 | — | — | |
| SCHEMBL46517 | 0.72 | — | — | |
| SCHEMBL25084356 | 0.65 | — | — | |
| SCHEMBL21940617 | 0.65 | — | — | |
| SCHEMBL20320575 | 0.65 | — | — | |
| SCHEMBL24173981 | 0.65 | — | — | |
| SCHEMBL21303783 | 0.65 | — | — | |
| SCHEMBL7054469 | 0.65 | — | — | |
| SCHEMBL18057555 | 0.65 | GAA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643923-A | TREATMENT OF ANXIETY, COGNITION ACTIVATORS, SENILITY OR ALZHEIMER'S | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0456519-B1 | Piperidyloxy- and quinuclidinyloxy- isoxazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-07-13 | — | — | EP | disclosed |
| CN-1057259-A | Piperidines oxygen base and quinine epoxy group(ing) different oxazole derivatives, their preparation and the application aspect treatment thereof | SANKYO CO (JP) | 1991-12-25 | — | — | CN | disclosed |
| EP-0456519-A1 | Piperidyloxy- and quinuclidinyloxy- isoxazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1991-11-13 | — | — | EP | disclosed |
| US-4247548-A | 7α-Methoxycephalosporin derivatives and their pharmaceutical compositions having antibacterial activity | SANKYO COMPANY LIMITED (JP) | 1981-01-27 | — | — | US | disclosed |
| US-4209512-A | INSECTICIDES, MITICIDES | SANKYO COMPANY LIMITED (JP) | 1980-06-24 | — | — | US | disclosed |
| US-4060402-A | HERBICIDE | SANKYO COMPANY LIMITED (JA) | 1977-11-29 | — | — | US | disclosed |
| US-4044018-A | Isoxazolone derivatives, their preparation and their use as plant growth regulators | SANKYO COMPANY LIMITED (JA) | 1977-08-23 | — | — | US | disclosed |