Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | PEPD | P12955 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285895 | 1.00 | ANPEP (0.42) | ANPEPDNPEPCYP2D6CYP2C19MAPT | |
| SCHEMBL7279294 | 0.81 | ANPEP (0.41) | ANPEPDNPEPCYP2D6CYP2C19MAPT | |
| SCHEMBL7288179 | 0.81 | ANPEP (0.41) | ANPEPDNPEPCYP2D6CYP2C19MAPT | |
| SCHEMBL7278906 | 0.78 | ANPEP (0.39) | ANPEPDNPEPCYP2D6CYP2C19MAPT | |
| SCHEMBL7284497 | 0.78 | ANPEP (0.39) | ANPEPDNPEPCYP2D6CYP2C19MAPT | |
| SCHEMBL7317760 | 0.76 | ANPEP (0.38) | ANPEPDNPEPCYP2D6CYP2C19MAPT | |
| SCHEMBL16160044 | 0.73 | CYP2D6 (0.48) | CYP2D6CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL7294441 | 0.72 | ANPEP (0.44) | ANPEPDNPEPCYP2D6CYP2C19MAPT | |
| SCHEMBL7287058 | 0.72 | ANPEP (0.44) | ANPEPDNPEPCYP2D6CYP2C19MAPT | |
| SCHEMBL10714554 | 0.68 | ANPEP (0.40) | ANPEPDNPEPCYP2D6RNPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272583-B1 | 5-SUBSTITUTED AMINO-4-HYDROXY-PENTENOIC ACID DERIVATIVES AND THEIR USE | Banyu Pharmaceutical Co., Ltd. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4927565-A | HYPOTENSIVE AGENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0272583-A2 | 5-Substituted amino-4-hydroxy-pentenoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-06-29 | — | — | EP | disclosed |