Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.74 |
| ▸ | RARB | P10826 | 3/20 | 0.70 |
| ▸ | THRA | P10827 | 1/20 | 0.67 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.67 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.67 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383674 | 1.00 | TP53 (0.77) | TP53TSHRPLA2G4BRARBTHRA | |
| SCHEMBL9325995 | 1.00 | TP53 (0.77) | TP53TSHRPLA2G4BRARBTHRA | |
| SCHEMBL14672324 | 1.00 | TP53 (0.77) | TP53TSHRPLA2G4BRARBTHRA | |
| SCHEMBL9779326 | 1.00 | TP53 (0.77) | TP53TSHRPLA2G4BRARBTHRA | |
| SCHEMBL7283625 | 1.00 | TP53 (0.77) | TP53TSHRPLA2G4BRARBTHRA | |
| SCHEMBL7281514 | 1.00 | TP53 (0.77) | TP53TSHRPLA2G4BRARBTHRA | |
| SCHEMBL7271669 | 1.00 | TP53 (0.77) | TP53TSHRPLA2G4BRARBTHRA | |
| SCHEMBL5388136 | 1.00 | TP53 (0.77) | TP53TSHRPLA2G4BRARBTHRA | |
| Hydrochloric Acid SCHEMBL8541196 | 0.98 | TP53 (0.74) | TP53TSHRPLA2G4BRARBTHRA | |
| Hydrochloric Acid SCHEMBL8302098 | 0.98 | TP53 (0.74) | TP53TSHRPLA2G4BRARBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3145444-A | — | — | None | — | — | JP | disclosed |
| CN-104211766-B | Six lipopeptide compound of ring and its purposes as drug | 中国人民解放军第二军医大学 | 2018-07-31 | — | — | CN | disclosed |
| CN-104211766-A | Cyclohexalipopeptide compounds and pharmaceutical application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2014-12-17 | — | — | CN | disclosed |
| CN-101602795-B | Cyclohexalipopeptide amine antifungal compound, salts and preparation method thereof | ARMY MEDICAL UNIV. NO.2, CHINESE PLA (CN) | 2011-12-21 | — | — | CN | disclosed |
| CN-101602795-A | Cyclohexalipopeptideamine amine antifungal compound and its esters and preparation method | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2009-12-16 | — | — | CN | disclosed |
| EP-0805685-B1 | NOVEL ANTIFUNGAL CYCLOHEXAPEPTIDES | MERCK & CO INC (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-0758013-B1 | Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display | NIPPON OIL CO LTD (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0779895-B1 | AN IMPROVED PROCESS FOR PREPARING SIDE CHAIN DERIVATIVES OF CYCLOHEXAPEPTIDYL LIPOPEPTIDES | MERCK & CO INC (US) | 1999-11-17 | — | — | EP | disclosed |
| US-5914313-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1999-06-22 | — | — | US | disclosed |
| US-5855971-A | Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film | NIPPON OIL COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | disclosed |
| CN-1059729-A | Novel polypeptide compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-03-25 | — | — | CN | disclosed |
| EP-0462531-A2 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-5072021-A | Liquid crystals | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-12-10 | — | — | US | disclosed |
| US-5061399-A | FERROELECTRICITY | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1991-10-29 | — | — | US | disclosed |
| JP-H03145444-A | NAPHTHALENE RING-CONTAINING LIQUID CRYSTAL COMPOUND | KASHIMA SEKIYU KK | 1991-06-20 | — | — | JP | disclosed |
| EP-0302875-B1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1991-02-27 | — | — | EP | disclosed |
| EP-0391956-A1 | CYANOHYDRIN DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES. | SECR DEFENCE BRIT (GB) | 1990-10-17 | — | — | EP | disclosed |
| WO-1989005792-A1 | CYANOHYDRIN DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1989-06-29 | — | — | WO | disclosed |
| EP-0302875-A1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM. | SECR DEFENCE BRIT (GB) | 1989-02-15 | — | — | EP | disclosed |
| WO-1987006577-A2 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1987-11-05 | — | — | WO | disclosed |