Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.89 |
| ▸ | BCHE | P06276 | 9/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | NPY1R | P25929 | 1/20 | 0.68 |
| ▸ | NPY2R | P49146 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19532604 | 0.94 | SLC2A1 (1.00) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| SCHEMBL7279743 | 0.94 | SLC2A1 (0.80) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| SCHEMBL19532621 | 0.87 | BCHE (1.00) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| SCHEMBL19532591 | 0.87 | BCHE (1.00) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| SCHEMBL29721229 | 0.87 | SLC2A1 (0.73) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| SCHEMBL14691619 | 0.87 | SLC2A1 (0.73) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| SCHEMBL10702781 | 0.87 | SLC2A1 (0.69) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| Hydrochloric Acid SCHEMBL29721109 | 0.85 | SLC2A1 (0.71) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| Hydrochloric Acid SCHEMBL18529888 | 0.85 | SLC2A1 (0.71) | SLC2A1BCHESMN1; SMN2HTTKDM4E | |
| SCHEMBL21427198 | 0.85 | SLC2A1 (0.71) | SLC2A1BCHESMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375668-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1990-06-27 | — | — | EP | disclosed |
| US-4885313-A | 3,4-Dihydroxyphenylethylamine derivatives and their use | FISONS PLC (GB) | 1989-12-05 | — | — | US | disclosed |
| US-4803225-A | Dihydroxy-phenethylamino compounds useful as pharmaceuticals | FISONS, PLC (GB) | 1989-02-07 | — | — | US | disclosed |
| US-4720586-A | Substituted 3,4-dihydroxy-phenylethylamino compounds | FISONS, PLC (GB) | 1988-01-19 | — | — | US | disclosed |
| EP-0142283-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1985-05-22 | — | — | EP | disclosed |