Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 12/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | THPO | P40225 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292732 | 0.96 | SRD5A1 (0.68) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL2292737 | 0.96 | SRD5A1 (0.68) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8571744 | 0.96 | SRD5A1 (0.68) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8722392 | 0.96 | SRD5A1 (0.68) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL9215335 | 0.93 | SRD5A1 (0.66) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL9215344 | 0.93 | SRD5A1 (0.66) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL9214030 | 0.91 | SRD5A1 (0.64) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL9214038 | 0.91 | SRD5A1 (0.64) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL11002519 | 0.91 | SRD5A1 (0.75) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL11002514 | 0.91 | SRD5A1 (0.75) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462936-A1 | SiRNA mediated post-transriptional gene-silencing of genes involved in alopecia | Gencia Corporation (US) | 2012-06-13 | — | — | EP | claimed |
| JP-4742023-B2 | — | — | 2011-08-10 | — | — | JP | claimed |
| US-7501515-B2 | Polymorphic form of 17-β-(N-ter. butyl carbamoyl)-4-aza-5-α-androst-1-en-3-one | DR. REDDY'S LABORATORIES LIMITED (IN) | 2009-03-10 | — | — | US | claimed |
| US-20070141009-A1 | Sirna mediated post-transriptional gene silencing of genes involved in alopecia | GENCIA CORPORATION | 2007-06-21 | — | — | US | claimed |
| WO-2004063331-A9 | SiRNA MEDIATED POST-TRANSRIPTIONAL GENE SILENCING OF GENES INVOLVED IN ALOPECIA | GENCIA CORP (US) | 2005-11-17 | — | — | WO | claimed |
| EP-1590430-A2 | SiRNA MEDIATED POST-TRANSRIPTIONAL GENE SILENCING OF GENES INVOLVED IN ALOPECIA | Gencia Corporation (US) | 2005-11-02 | — | — | EP | claimed |
| WO-2004063331-A2 | SiRNA MEDIATED POST-TRANSRIPTIONAL GENE SILENCING OF GENES INVOLVED IN ALOPECIA | GENCIA CORPORATION (US) | 2004-07-29 | — | — | WO | claimed |
| EP-2462936-A1 | SiRNA mediated post-transriptional gene-silencing of genes involved in alopecia | Gencia Corporation (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20070141009-A1 | Sirna mediated post-transriptional gene silencing of genes involved in alopecia | GENCIA CORPORATION | 2007-06-21 | — | — | US | disclosed |
| EP-1504021-A1 | PROCESS FOR DEHYDROGENATION OF AZAANDROSTANE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003095472-A1 | PROCESS FOR DEHYDROGENATION OF AZAANDROSTANE COMPOUNDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-11-20 | — | — | WO | disclosed |
| US-5670643-A | Method for preparing finasteride | GLAXO WELLCOME INC. (US) | 1997-09-23 | — | — | US | disclosed |