Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ARG1 | P05089 | 6/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348716 | 1.00 | SLC1A2 (0.52) | SLC1A2MEN1BLMKMT2AARG1 | |
| SCHEMBL10680722 | 1.00 | SLC1A2 (0.52) | SLC1A2MEN1BLMKMT2AARG1 | |
| SCHEMBL7346916 | 1.00 | SLC1A2 (0.52) | SLC1A2MEN1BLMKMT2AARG1 | |
| Hydrochloric Acid SCHEMBL202139 | 0.98 | SLC1A2 (0.50) | SLC1A2MEN1BLMKMT2AARG1 | |
| Hydrochloric Acid SCHEMBL26117737 | 0.98 | SLC1A2 (0.50) | SLC1A2MEN1BLMKMT2AARG1 | |
| Trifluoroacetic Acid SCHEMBL18614506 | 0.89 | SLC1A2 (0.43) | SLC1A2MEN1BLMKMT2AARG1 | |
| SCHEMBL9939298 | 0.88 | MEN1 (0.55) | SLC1A2MEN1BLMKMT2AARG1 | |
| SCHEMBL30556916 | 0.82 | SLC1A2 (0.36) | SLC1A2MEN1BLMKMT2A | |
| SCHEMBL1485663 | 0.82 | SLC1A2 (0.41) | SLC1A2MEN1BLMKMT2AARG1 | |
| SCHEMBL29039338 | 0.82 | SLC1A2 (0.36) | SLC1A2MEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4316906-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |