Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.80 |
| ▸ | ACE | P12821 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ECE1 | P42892 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068900 | 1.00 | MME (0.80) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7273423 | 1.00 | MME (0.80) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL387085 | 1.00 | MME (0.80) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL3631586 | 0.99 | MME (0.82) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7271591 | 0.94 | MME (0.84) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7281509 | 0.89 | MME (0.71) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL389731 | 0.89 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL29494162 | 0.89 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL3623644 | 0.85 | MME (0.68) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL3623638 | 0.85 | MME (0.72) | MMEACEALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| US-4798904-A | ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1989-01-17 | — | — | US | disclosed |
| US-4774256-A | MERCAPTO AND ACYLMERCAPTO AMIDES | E. R. SQUIBB & SONS, INC. (US) | 1988-09-27 | — | — | US | disclosed |
| US-4722810-A | Enkephalinase inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1988-02-02 | — | — | US | disclosed |
| EP-0136883-B1 | ENKEPHALINASE INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1987-11-25 | — | — | EP | disclosed |
| EP-0136883-A2 | Enkephalinase inhibitors | E.R. Squibb & Sons, Inc. (US) | 1985-04-10 | — | — | EP | disclosed |