Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280855 | 0.90 | ELANE (0.78) | ELANE | |
| SCHEMBL7288393 | 0.90 | ELANE (0.77) | ELANE | |
| Hydrochloric Acid SCHEMBL7281814 | 0.90 | ELANE (0.77) | ELANE | |
| SCHEMBL7436955 | 0.88 | ELANE (1.00) | ELANE | |
| SCHEMBL7281182 | 0.87 | ELANE (0.92) | ELANE | |
| Hydrochloric Acid SCHEMBL7288631 | 0.86 | ELANE (0.90) | ELANE | |
| SCHEMBL7305284 | 0.85 | ELANE (1.00) | ELANE | |
| Hydrochloric Acid SCHEMBL7314311 | 0.84 | ELANE (0.99) | ELANE | |
| SCHEMBL7437415 | 0.83 | ELANE (1.00) | ELANE | |
| SCHEMBL7429604 | 0.83 | ELANE (0.77) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597841-A | 2-saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP, INC. (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0594257-B1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC (US) | 1996-07-10 | — | — | EP | disclosed |
| EP-0594257-A1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5306818-A | Treating degenerative diseases such as emphysema, rheumatoid arthritis and pancreatitis | STERLING WINTHROP INC. (US) | 1994-04-26 | — | — | US | disclosed |