⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840266 | 0.97 | — | — | |
| SCHEMBL2394128 | 0.92 | — | — | |
| SCHEMBL2389506 | 0.92 | — | — | |
| SCHEMBL153331 | 0.92 | — | — | |
| SCHEMBL839731 | 0.83 | — | — | |
| SCHEMBL2836847 | 0.80 | — | — | |
| SCHEMBL1866108 | 0.79 | — | — | |
| SCHEMBL8151949 | 0.78 | EPHX1 (0.41) | — | |
| SCHEMBL6646897 | 0.78 | KMT2A (0.38) | — | |
| SCHEMBL4090573 | 0.77 | EPHX1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 684 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | HOFFMANN-LA ROCHE INC. (US) | 2022-06-07 | — | — | US | claimed |
| CN-114478506-A | Pyridine oxazole compound and application thereof | 东莞市东阳光农药研发有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-108026077-B | Phenoxymethyl derivatives | 豪夫迈·罗氏有限公司 | 2021-11-05 | — | — | CN | claimed |
| EP-3344619-B1 | PHENOXYMETHYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-10-28 | — | — | EP | claimed |
| CN-107624113-B | Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of HBsAg (HBV surface antigen) and HBV DNA production for the treatment of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-107835813-B | 6, 7-dihydropyrido [2,1-a ] phthalazin-2-ones for the treatment and prevention of hepatitis b virus infections | 豪夫迈·罗氏有限公司 | 2020-04-24 | — | — | CN | claimed |
| EP-3292120-B1 | TETRAHYDROPYRIDOPYRIMIDINES AND TETRAHYDROPYRIDOPYRIDINES AS INHIBITORS OF HBSAG (HBV SURFACE ANTIGEN) AND HBV DNA PRODUCTION FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTIONS | HOFFMANN LA ROCHE (CH) | 2019-06-19 | — | — | EP | claimed |
| EP-3328858-B1 | NOVEL 6,7-DIHYDROPYRIDO[2,1-A]PHTHALAZIN-2-ONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2019-05-15 | — | — | EP | claimed |
| US-10150740-B2 | 6,7-dihydropyrido[2,1-A]phthalazin-2-ones for the treatment and prophylaxis of hepatitis B virus infection | HOFFMANN-LA ROCHE INC. (US) | 2018-12-11 | — | — | US | claimed |
| US-20180201588-A1 | PHENOXYMETHYL DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2018-07-19 | — | — | US | claimed |
| WO-1995031440-A1 | SUBSTITUTED DIAZACYCLOHEXANDI(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-23 | — | — | WO | claimed |
| WO-1995030661-A1 | SUBSTITUTED AROMATIC THIOCARBOXYLIC ACID AMIDES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-16 | — | — | WO | claimed |
| EP-0631575-A1 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1995-01-04 | — | — | EP | claimed |
| WO-1994021613-A1 | CONDENSED NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS, FUNGICIDES AND ANTIMYCOTICS | HOECHST SCHERING AGREVO GMBH (DE) | 1994-09-29 | — | — | WO | claimed |
| EP-0345597-B1 | O-halo-cyclobutyl-S-alkyl-(di)thiophosphonic(phosphoric) acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1993-10-27 | — | — | EP | claimed |
| WO-1993019050-A1 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1993-09-30 | — | — | WO | claimed |
| US-4973583-A | Pesticidal O-halogenocyclobutyl S-alkyl (di)thiphosph)(on)ates | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | claimed |
| EP-0345597-A2 | O-halo-cyclobutyl-S-alkyl-(di)thiophosphonic(phosphoric) acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1989-12-13 | — | — | EP | claimed |
| EP-0067382-B1 | N-CYCLOHEXYL-CHLOROACETAMIDES, THEIR PREPARATION AND THEIR USE IN COMBATING UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1985-12-04 | — | — | EP | claimed |
| US-4525203-A | ((3,4,5,6-Tetrahydro-2H-pyran-2-yl)methoxy)oxabicycloalkane herbicides | SHELL OIL COMPANY (US) | 1985-06-25 | — | — | US | claimed |