Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL478157 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL96757 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL22022 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL5792283 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL29074494 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL11296805 | 0.90 | — | — | |
| SCHEMBL13208844 | 0.89 | — | — | |
| SCHEMBL8227653 | 0.89 | — | — | |
| SCHEMBL15047 | 0.89 | — | — | |
| Water SCHEMBL1245230 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3755148-A1 | NANOSUSPENSIONS OF SALSALATE AND METHODS OF USING THE SAME | RHNanoPharma (US) | 2020-12-30 | — | — | EP | claimed |
| WO-2019165240-A1 | NANOSUSPENSIONS OF SALSALATE AND METHODS OF USING THE SAME | RHNANOPHARMA (US) | 2019-08-29 | — | — | WO | claimed |
| US-20150320682-A1 | NANOPARTICULATE MEGESTROL FORMULATIONS | ALKERMES PHARMA IRELAND LIMITED (IE) | 2015-11-12 | — | — | US | claimed |
| EP-2435027-A2 | REDUCTION OF FLAKE-LIKE AGGREGATION IN NANOPARTICULATE ACTIVE AGENT COMPOSITIONS | Alkermes Pharma Ireland Limited (IE) | 2012-04-04 | — | — | EP | claimed |
| JP-4831965-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| EP-1553927-B9 | GEL-STABILIZED NANOPARTICULATE ACTIVE AGENT COMPOSITIONS | ELAN PHARMA INT LTD (IE) | 2011-09-21 | — | — | EP | claimed |
| WO-2010138539-A2 | REDUCTION OF FLAKE-LIKE AGGREGATION IN NANOPARTICULATE ACTIVE AGENT COMPOSITIONS | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2010-12-02 | — | — | WO | claimed |
| EP-1553927-B1 | GEL-STABILIZED NANOPARTICULATE ACTIVE AGENT COMPOSITIONS | ELAN PHARMA INT LTD (IE) | 2010-11-10 | — | — | EP | claimed |
| EP-2230906-A1 | NANOPARTICULATE ANIDULAFUNGIN COMPOSITIONS AND METHODS FOR MAKING THE SAME | Elan Pharma International Limited (IE) | 2010-09-29 | — | — | EP | claimed |
| WO-2009114695-A1 | NANOPARTICULATE COMPOSITIONS OF ANGIOGENESIS INHIBITORS | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2009-09-17 | — | — | WO | claimed |
| WO-2004032980-A1 | GAMMA IRRADIATION OF SOLID NANOPARTICULATE ACTIVE AGENTS | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2004-04-22 | — | — | WO | claimed |
| WO-2003103640-A1 | NANOPARTICULATE FORMULATIONS COMPRISING HMG COA REDUCTASE INHIBITOR DERIVATIVES (“STATINS”), NOVEL COMBINATIONS THEREOF AS WELL AS MANUFACTURING OF THESE PHARMACEUTICAL COMPOSITIONS | ELAN PHARMA INTERNATIONAL, LTD (IE) | 2003-12-18 | — | — | WO | claimed |
| WO-2003103632-A1 | NANOPARTICULATE POLYCOSANOL FORMULATIONS AND NOVEL POLYCOSANOL COMBINATIONS | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2003-12-18 | — | — | WO | claimed |
| WO-2003103633-A1 | NANOPARTICULATE STEROL FORMULATIONS AND STEROL COMBINATIONS | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2003-12-18 | — | — | WO | claimed |
| WO-2003094894-A1 | NANOPARTICULATE NYSTATIN FORMULATIONS | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-11-20 | — | — | WO | claimed |
| WO-2003086354-A1 | NANOPARTICULATE MEGESTROL FORMULATIONS | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-10-23 | — | — | WO | claimed |
| WO-2003080024-A2 | NANOPARTICULATE COMPOSITIONS OF MAP KINASE INHIBITORS | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2003-10-02 | — | — | WO | claimed |
| WO-2003080027-A1 | NANOPARTICULATE COMPOSITIONS OF ANGIOGENESIS INHIBITORS | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2003-10-02 | — | — | WO | claimed |
| WO-2003080023-A2 | FAST DISSOLVING DOSAGE FORMS HAVING REDUCED FRIABILITY | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2003-10-02 | — | — | WO | claimed |
| WO-2003030872-A2 | COMPOSITIONS HAVING A COMBINATION OF PARTICLES FOR IMMEDIATE RELEASE AND FOR CONTROLLED RELEASE | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-04-17 | — | — | WO | claimed |