SCHEMBL728204

SCHEMBL728204

CCCCCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 3/20 0.46
TSHR P16473 3/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KCNH2 Q12809 2/20 0.43
KDM4E B2RXH2 1/20 0.43
TLR8 Q9NR97 7/20 0.41
LIPG Q9Y5X9 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
ALOX5 P09917 2/20 0.39
PTGS2 P35354 1/20 0.39
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9299020 0.98 MEN1 (0.59) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL9445539 0.98 MEN1 (0.59) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL28012082 0.98 MEN1 (0.59) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL8684572 0.98 MEN1 (0.59) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL30345593 0.98 MEN1 (0.59) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL9058783 0.98 MEN1 (0.59) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL9931458 0.98 MEN1 (0.59) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL4585929 0.98 MEN1 (0.59) MEN1KMT2AALDH1A1CYP3A4TSHR
Methane SCHEMBL26103663 0.97 MEN1 (0.58) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL29743239 0.95 MEN1 (0.63) MEN1KMT2AALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978642-B2 Mixture, composition and organic electronic device GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2021-04-13 US claimed
EP-3553152-B1 MIXTURE, COMPOSITION AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MAT LTD (CN) 2021-02-17 EP claimed
US-20200098992-A1 MIXTURE, COMPOSITION AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2020-03-26 US claimed
EP-3553152-A1 MIXTURE, COMPOSITION AND ORGANIC ELECTRONIC DEVICE Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2019-10-16 EP claimed
CN-109790461-A Mixture, composition and organic electronic device 广州华睿光电材料有限公司 2019-05-21 CN claimed
CN-103539725-B Four aryl pyrene analog derivatives, preparation method and application and electroluminescent device TCL Research America Inc. (CN) 2016-02-10 CN claimed
CN-103539725-A Tetra-aryl pyrene derivative, preparation method and application thereof and electroluminescent device TCL GROUP CO LTD 2014-01-29 CN claimed
CN-101897051-B Phosphorescent OLED device with certain fluoranthene host GLOBAL OLED TECHNOLOGY LLC 2013-01-02 CN claimed
CN-101897051-A Phosphorescent OLED device with certain fluoranthene host EASTMAN KODAK CO 2010-11-24 CN claimed
EP-0892774-A4 PYRONIN ANTIBACTERIALS, PROCESS AND NOVEL INTERMEDIATES THERETO ANADYS PHARMACEUTICALS INC (US) 2001-10-04 EP claimed
CN-1054851-C 3-aryl-pyrone derivatives BAYER AG (DE) 2000-07-26 CN claimed
US-6090953-A PREPARING A MYXOPYRONIN SCRIPTGEN PHARMACEUTICALS, INC. (US) 2000-07-18 US claimed
WO-2000015626-A1 PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR PYRONIN ANTIBACTERIALS ANADYS PHARMACEUTICALS, INC. (US) 2000-03-23 WO claimed
US-5986111-A CONDENSATION OF ALDEHYDE WITH PYRONE TO FORM ADDUCT, OXIDATION AND SAPONIFICATION SCRIPTGEN PHARMACEUTICALS, INC. (US) 1999-11-16 US claimed
EP-0588137-B1 3-Aryl-2-pyranone derivatives BAYER AG (DE) 1999-02-03 EP claimed
EP-0892774-A2 PYRONIN ANTIBACTERIALS, PROCESS AND NOVEL INTERMEDIATES THERETO SCRIPTGEN PHARMACEUTICALS, INC. (US) 1999-01-27 EP claimed
US-5763128-A Simulated photographic-quality images on a substrate without curl XEROX CORPORATION (US) 1998-06-09 US claimed
WO-1997034569-A2 PYRONIN ANTIBACTERIALS, PROCESS AND INTERMEDIATES SCRIPTGEN PHARMACEUTICALS, INC. (US) 1997-09-25 WO claimed
US-5393729-A Pesticides, fungicides, herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-02-28 US claimed
CN-1085554-A 3-Arylpyrone Derivatives BAYER AG (DE) 1994-04-20 CN claimed