SCHEMBL7283202

SCHEMBL7283202

COc1cccc(CCc2c(CCNCCCCCCNCCC3CCCCC3)ccc(OC)c2OC)c1

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 3/20 0.72
CHRM2 P08172 1/20 0.43
BCHE P06276 1/20 0.41
ABCB1 P08183 2/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10383116 0.99 SLC2A1 (0.74) SLC2A1CHRM2BCHEABCB1ABCG2
Hydrochloric Acid SCHEMBL7293232 0.88 SLC2A1 (0.59) SLC2A1CHRM2BCHE
Hydrochloric Acid SCHEMBL7286739 0.87 SLC2A1 (0.94) SLC2A1CHRM2BCHEABCB1ABCG2
SCHEMBL7295425 0.85 SLC2A1 (0.98) SLC2A1CHRM2BCHEABCB1ABCG2
Hydrochloric Acid SCHEMBL7284944 0.84 SLC2A1 (1.00) SLC2A1CHRM2BCHEABCB1ABCG2
Hydrochloric Acid SCHEMBL10383816 0.84 SLC2A1 (1.00) SLC2A1CHRM2BCHEABCB1ABCG2
Hydrochloric Acid SCHEMBL7446538 0.84 SLC2A1 (1.00) SLC2A1CHRM2BCHEABCB1ABCG2
Hydrochloric Acid SCHEMBL7501183 0.84 SLC2A1 (1.00) SLC2A1CHRM2BCHEABCB1ABCG2
Hydrochloric Acid SCHEMBL7434415 0.84 SLC2A1 (1.00) SLC2A1CHRM2BCHEABCB1ABCG2
Hydrochloric Acid SCHEMBL7292844 0.84 SLC2A1 (0.85) SLC2A1CHRM2BCHEABCB1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0223598-B1 CATECHOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF FISONS plc (GB) 1991-06-12 EP disclosed
US-4883804-A Aromatic compounds FISONS PLC (GB) 1989-11-28 US disclosed