Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193513 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL1203937 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL132349 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL15328461 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL9568635 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL7105559 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL10483782 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL8058978 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL10483779 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL9717667 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117257794-A | Application of pleuromutilin derivative with side chain containing nitrogen heterocycle or alkylamine in preparation of drug for preventing and treating mycoplasma gallisepticum | 华南农业大学 | 2023-12-22 | — | — | CN | disclosed |
| US-4668683-A | Cardiotonic quinazoline derivatives | KYOWA HAKKO KOGYO K.K. (JP) | 1987-05-26 | — | — | US | disclosed |
| EP-0195667-A2 | Cardiotonic quinazoline derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1986-09-24 | — | — | EP | disclosed |