Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281650 | 1.00 | CHRM4 (0.37) | CHRM4LMNAOPRM1OPRD1MDM2 | |
| SCHEMBL7281644 | 1.00 | CHRM4 (0.37) | CHRM4LMNAOPRM1OPRD1MDM2 | |
| SCHEMBL7283087 | 0.92 | KDM1A (0.39) | CHRM4LMNAOPRM1OPRD1HPGD | |
| SCHEMBL7284971 | 0.92 | KDM1A (0.39) | CHRM4LMNAOPRM1OPRD1HPGD | |
| SCHEMBL7283082 | 0.92 | KDM1A (0.39) | CHRM4LMNAOPRM1OPRD1HPGD | |
| SCHEMBL7282695 | 0.84 | KDM1A (0.41) | CHRM4LMNAOPRM1OPRD1HPGD | |
| SCHEMBL8881618 | 0.84 | KDM1A (0.41) | CHRM4LMNAOPRM1OPRD1HPGD | |
| SCHEMBL7275921 | 0.84 | KDM1A (0.41) | CHRM4LMNAOPRM1OPRD1HPGD | |
| SCHEMBL7281636 | 0.83 | MDM2 (0.37) | MDM2TP53DGAT1 | |
| SCHEMBL7284736 | 0.83 | MDM2 (0.37) | MDM2TP53DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |