Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284948 | 1.00 | TSHR (0.37) | TSHRMEN1KMT2ACYP3A4ASAH2 | |
| SCHEMBL7294233 | 0.88 | TRPV1 (0.44) | MEN1KMT2ACYP3A4TRPV1F7 | |
| SCHEMBL7294239 | 0.88 | TRPV1 (0.44) | MEN1KMT2ACYP3A4TRPV1F7 | |
| SCHEMBL7298667 | 0.81 | TRPV1 (0.50) | TSHRCYP3A4TRPV1F7F3 | |
| SCHEMBL7298670 | 0.81 | TRPV1 (0.50) | TSHRCYP3A4TRPV1F7F3 | |
| SCHEMBL28699442 | 0.78 | TSHR (0.37) | TSHRMEN1KMT2ACYP3A4ASAH2 | |
| SCHEMBL2164195 | 0.77 | — | — | |
| SCHEMBL7550135 | 0.75 | — | — | |
| SCHEMBL7550132 | 0.75 | — | — | |
| SCHEMBL2003208 | 0.75 | MEN1 (0.39) | TSHRMEN1KMT2ACYP3A4ASAH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |