SCHEMBL728552

SCHEMBL728552

Cc1c[nH]c(C2CCCCC2)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
EPHX2 P34913 1/20 0.35
MAPT P10636 1/20 0.35
GFER P55789 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34
CCNE1 P24864 2/20 0.33
CDK2 P24941 2/20 0.33
LMNA P02545 1/20 0.33
ADORA1 P30542 1/20 0.33
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
TYK2 P29597 1/20 0.33
JAK3 P52333 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15724298 0.98 NPC1 (0.40) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL28527650 0.94 NPC1 (0.37) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL15724292 0.90
SCHEMBL1299331 0.82 HTR2C (0.41)
SCHEMBL15108932 0.80 ADORA1 (0.31) NPC1RAB9AADORA1
SCHEMBL14826727 0.79 IRAK4 (0.36) JAK2JAK1TYK2
SCHEMBL5302092 0.78 KDM4E (0.42) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL11127892 0.76 KDM4E (0.41) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL27757639 0.76 KDM4E (0.41) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL19625283 0.76 NPC1 (0.40) NPC1RAB9AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2585473-B1 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF ICL IP AMERICA INC (US) 2015-09-23 EP claimed
US-8889773-B2 Metal phosphonate flame retardant and method producing thereof ICL-IP AMERICA INC. (US) 2014-11-18 US claimed
US-20130165564-A1 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF ICL-IP AMERICA INC. (US) 2013-06-27 US claimed
EP-2585473-A2 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF ICL-IP America Inc. (US) 2013-05-01 EP claimed
CN-103003289-A Metal Phosphonate Flame Retardant And Method Producing Thereof ICL IP AMERICA INC 2013-03-27 CN claimed
WO-2011163207-A2 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF ICL-IP AMERICA INC. (US) 2011-12-29 WO claimed
CN-100340604-C Thermosetting resin composition for high-speed transmission circuit board LG CHEMICAL LTD (KR) 2007-10-03 CN claimed
US-7255925-B2 Thermosetting resin composition for high speed transmission circuit board LG CHEM, LTD. (KR) 2007-08-14 US claimed
JP-2006518774-A 2006-08-17 JP claimed
CN-1701093-A Thermosetting resin composition for high speed transmission circuit board LG CHEMICAL LTD (KR) 2005-11-23 CN claimed
CN-1150244-C Epoxy resin compsn. and laminate using same LG��ѧ��ʽ���� 2004-05-19 CN claimed
US-6703124-B2 COPPER THIN FILM LAMINATE; NONFLAMMABLE; HEAT RESISTANCE LG CHEMICAL CO., LTD. (KR) 2004-03-09 US claimed
US-20030054146-A1 Epoxy resin composition and laminate using the same LG CHEMICAL CO., LTD. (KR) 2003-03-20 US claimed
CN-1383436-A Epoxy resin compsn. and laminate using same LG CHEMICAL LTD (KR) 2002-12-04 CN claimed
WO-2001096440-A1 EPOXY RESIN COMPOSITION AND LAMINATE USING THE SAME LG CHEMICAL CO., LTD. (KR) 2001-12-20 WO claimed
EP-0866819-B1 METHOD FOR PREPARING A CURING AGENT FOR EPOXY RESINS MINNESOTA MINING & MFG (US) 2000-01-26 EP claimed
EP-0866819-A1 METHOD FOR PREPARING A CURING AGENT FOR EPOXY RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-09-30 EP claimed
US-5801218-A IMIDAZOLE-EPOXY ADDUCTS AS CURING AGENTS FOR EPOXY RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-09-01 US claimed
US-5717011-A AGITATING MIXTURE OF EPOXY COMPOUND, IMIDAZOLE COMPOUND AND WATER WITH HEATING TO FORM CURING AGENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-02-10 US claimed
WO-1997021751-A1 METHOD FOR PREPARING A CURING AGENT FOR EPOXY RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-06-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165564-A1 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF MTAP, AS3MT, MPHOSPH6 NPC1 4578/4885RAB9A 1377/4885KDM4E 693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.