⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452286 | 0.80 | — | — | |
| SCHEMBL5683458 | 0.71 | — | — | |
| SCHEMBL18092331 | 0.71 | — | — | |
| SCHEMBL15273455 | 0.69 | — | — | |
| SCHEMBL1082977 | 0.69 | — | — | |
| SCHEMBL9950729 | 0.67 | — | — | |
| SCHEMBL16266148 | 0.67 | — | — | |
| SCHEMBL5915961 | 0.67 | — | — | |
| SCHEMBL7111848 | 0.67 | — | — | |
| SCHEMBL7671823 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4831865-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| EP-1272233-B1 | INJECTABLE INTRAOCULAR LENS | AMO GRONINGEN BV (NL) | 2005-08-31 | — | — | EP | claimed |
| US-6613343-B2 | Polysiloxanes, having a specific gravity of greater than 1.0, a refractive index suitable for restoring the refractive power of the natural crystalline lens and a viscosity suitable for injection | PHARMACIA GRONINGEN BV (NL) | 2003-09-02 | — | — | US | claimed |
| EP-1272233-A1 | INJECTABLE INTRAOCULAR LENS | Pharmacia Groningen B.V. (NL) | 2003-01-08 | — | — | EP | claimed |
| JP-2002527170-A | — | — | 2002-08-27 | — | — | JP | claimed |
| US-20020071856-A1 | Injectable intraocular accommodating lens | ADVANCED MEDICAL OPTICS, INC. | 2002-06-13 | — | — | US | claimed |
| US-20020055778-A1 | Injectable intraocular lens | ADVANCED MEDICAL OPTICS, INC. | 2002-05-09 | — | — | US | claimed |
| US-6361561-B1 | POLYSILOXANE | PHARMACIA & UPJOHN AB (SE) | 2002-03-26 | — | — | US | claimed |
| WO-2001076651-A1 | INJECTABLE INTRAOCULAR LENS | PHARMACIA GRONINGEN BV (NL) | 2001-10-18 | — | — | WO | claimed |
| EP-1141751-A1 | INJECTABLE INTRAOCULAR LENS | Pharmacia Groningen B.V. (NL) | 2001-10-10 | — | — | EP | claimed |
| WO-2000022459-A1 | INJECTABLE INTRAOCULAR LENS | PHARMACIA GRONINGEN BV (NL) | 2000-04-20 | — | — | WO | claimed |
| EP-1137955-B1 | PHOTOCURABLE SILOXANE POLYMERS | AMO GRONINGEN BV (NL) | 2013-01-02 | — | — | EP | disclosed |
| US-6737496-B2 | POLYSILOXANE COPOLYMER HAVING FUNCTIONAL ACRYL GROUPS CAPABLE OF BEING PHOTOPOLYMERIZED INTO A SOLID INTRAOCULAR LENS | PHARMACIA GRONINGEN BV (NL) | 2004-05-18 | — | — | US | disclosed |
| US-20030088044-A1 | Photocurable siloxane polymers | ADVANCED MEDICAL OPTICS, INC. | 2003-05-08 | — | — | US | disclosed |
| US-6399734-B1 | INJECTABLE LENS MATERIAL; MIXTURE OF SILOXANE COPOLYMER, PHOTOINITIATOR | PHARMACIA AB (SE) | 2002-06-04 | — | — | US | disclosed |
| EP-1137955-A1 | PHOTOCURABLE SILOXANE POLYMERS | Pharmacia Groningen B.V. (NL) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000022460-A1 | PHOTOCURABLE SILOXANE POLYMERS | PHARMACIA GRONINGEN BV (NL) | 2000-04-20 | — | — | WO | disclosed |