SCHEMBL7286292

SCHEMBL7286292

O=CCCC1CNCCO1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 16/20 0.39
SLC6A4 P31645 14/20 0.39
SLC6A3 Q01959 9/20 0.39
HTR2A P28223 3/20 0.36
ADRB2 P07550 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
ADRA2C P18825 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17131022 1.00 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3HTR2AADRB2
SCHEMBL28483406 0.87 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3HTR2AADRB2
SCHEMBL1746181 0.81 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3HTR2AADRB2
SCHEMBL10512086 0.80 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3HTR2AADRB2
SCHEMBL15173596 0.80
SCHEMBL19387689 0.78 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3HTR2AADRB2
SCHEMBL197402 0.78
SCHEMBL20878691 0.78
SCHEMBL14474333 0.78
SCHEMBL10916638 0.78 BRD4 (0.36) SLC6A2SLC6A4SLC6A3HTR2AADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735565-A Method for continuously preparing 3-methyl-4-morpholinyl cyclobutanecarboxylic acid methyl ester 宁夏瑞泰科技股份有限公司 2025-04-01 CN disclosed
CN-119707796-A Continuous synthesis system and method for 2-chloro-5-methylpyridine 宁夏瑞泰科技股份有限公司 2025-03-28 CN disclosed
CN-111499611-B Pyridine formyl aryl heteroaryl alpha-substituted amino acid compound, preparation method and application thereof 中国医学科学院放射医学研究所 2023-06-06 CN disclosed
CN-110577491-B Method for preparing 2-chloro-5-chloromethyl pyridine 西安凯立新材料股份有限公司 2021-01-08 CN disclosed
CN-108997203-B Efficient purification method of 2, 3-dichloro-5-trifluoromethylpyridine 江苏扬农化工集团有限公司 2020-08-14 CN disclosed
EP-3122747-B1 DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS NORTH & SOUTH BROTHER PHARMACY INVESTMENT CO LTD (CN) 2020-05-20 EP disclosed
CN-108467357-B Method for preparing 2-chloro-5-methylpyridine 江苏扬农化工集团有限公司 2020-04-17 CN disclosed
CN-110577491-A method for preparing 2-chloro-5-chloromethyl pyridine 西安凯立新材料股份有限公司 2019-12-17 CN disclosed
EP-3074394-B1 PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2019-02-20 EP disclosed
US-5652247-A VASOPRESSIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD (JP) 1997-07-29 US disclosed
US-5436254-A Vaopressin antagonists OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1995-07-25 US disclosed
EP-0602209-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-22 EP disclosed
EP-0382185-B1 Carbostyril derivatives OTSUKA PHARMA CO LTD (JP) 1994-06-15 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
CN-1046529-A Carbostyril derivative OTSUKA PHARMA CO LTD (JP) 1990-10-31 CN disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed