Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967849 | 0.77 | HRH3 (0.48) | HRH3POLBMAPTLMNAKMT2A | |
| SCHEMBL153467 | 0.76 | POLB (0.81) | HRH3POLBMAPTALDH1A1PKM | |
| SCHEMBL1037242 | 0.76 | HRH3 (0.48) | HRH3POLBMAPTALDH1A1PKM | |
| SCHEMBL64284 | 0.76 | POLB (0.81) | HRH3POLBMAPTALDH1A1PKM | |
| SCHEMBL1036468 | 0.76 | HRH3 (0.48) | HRH3POLBMAPTALDH1A1PKM | |
| SCHEMBL25432585 | 0.76 | HRH3 (0.48) | HRH3POLBMAPTALDH1A1PKM | |
| SCHEMBL5807815 | 0.76 | HRH3 (0.48) | HRH3POLBMAPTALDH1A1PKM | |
| SCHEMBL15650449 | 0.76 | POLB (0.81) | HRH3POLBMAPTALDH1A1PKM | |
| SCHEMBL20858732 | 0.76 | HRH3 (0.48) | HRH3POLBMAPTALDH1A1PKM | |
| SCHEMBL968654 | 0.76 | HRH3 (0.48) | HRH3POLBMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883797-A | CARDIOVASCULAR PROPERTIES; INCREASING CEREBRAL FLOW | FERRER INTERNACIONAL, S.A. (ES) | 1989-11-28 | — | — | US | disclosed |
| EP-0097340-A2 | Piperazine derivatives, a process for preparing them and pharmaceutical compositions | FERRER INTERNACIONAL, S.A. (ES) | 1984-01-04 | — | — | EP | disclosed |