Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 10/20 | 0.56 |
| ▸ | CACNA1D | Q01668 | 10/20 | 0.56 |
| ▸ | CACNA1S | Q13698 | 10/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 10/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286542 | 1.00 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9123056 | 0.95 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9032405 | 0.94 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10391376 | 0.94 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7275483 | 0.94 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL11688660 | 0.92 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL11688678 | 0.92 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL11687260 | 0.90 | MAPT (0.70) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL11687126 | 0.89 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9033028 | 0.89 | CYP1A2 (0.72) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494816-B1 | 1,4-Dihydropyridine derivatives, process for their preparation and therapeutical composition containing them | LAFON LABOR (FR) | 1999-07-21 | — | — | EP | disclosed |
| US-5475111-A | Process for the preparation of dihydropyridinecarboxylic acids | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-12-12 | — | — | US | disclosed |
| US-4994461-A | Vasodilators; treating cardiovascular disorders | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-02-19 | — | — | US | disclosed |
| EP-0240398-A1 | Dissymmetrical 1,4-dihydropyridine-3,5-dicarboxylic-acid derivatives, preparation processes and therapeutical use | FOURNIER INNOVATION ET SYNERGIE (FR) | 1987-10-07 | — | — | EP | disclosed |
| US-4021434-A | CEREBRAL VASODILATORS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |