Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288623 | 0.84 | MAOB (0.63) | MAOB | |
| SCHEMBL22304501 | 0.83 | MAOB (0.63) | MAOB | |
| SCHEMBL517561 | 0.82 | MAOB (0.74) | MAOB | |
| SCHEMBL9667797 | 0.82 | MAOB (0.57) | MAOB | |
| SCHEMBL22304755 | 0.81 | MAOB (0.61) | MAOB | |
| SCHEMBL10806139 | 0.81 | MAOB (0.56) | MAOB | |
| SCHEMBL10800830 | 0.79 | MAOB (0.57) | MAOB | |
| SCHEMBL9668897 | 0.78 | MAOB (0.56) | MAOB | |
| SCHEMBL22288965 | 0.76 | MAOB (0.56) | MAOB | |
| SCHEMBL22304801 | 0.75 | MAOB (0.53) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383449-B1 | Pyridazinone derivatives and processes for preparing the same | ORION YHTYMAE OY (FI) | 1995-09-06 | — | — | EP | disclosed |
| US-5185332-A | Treating congestive heart failure | ORION-YHTYMA OY (FI) | 1993-02-09 | — | — | US | disclosed |
| US-5122524-A | Treatment for congestive heart failure; hypertensive agents; vasodilation | ORION-YHTYMA OY (FI) | 1992-06-16 | — | — | US | disclosed |
| EP-0223937-B1 | INDOLES SUBSTITUTED WITH HETEROCYCLES, INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-5019575-A | Congestive Heart Failure Treatment | ORION-YHTYMA OY (FI) | 1991-05-28 | — | — | US | disclosed |
| EP-0383449-A2 | Pyridazinone derivatives and processes for preparing the same | ORION-YHTYMÀ OY (FI) | 1990-08-22 | — | — | EP | disclosed |
| US-4851406-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-25 | — | — | US | disclosed |
| US-4683232-A | N,N-DIMETHYL-P-(2,3-DIHYDRO-2-OXO-6H-1,3,4 OXADIAZIN-2-YLBENZAMIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-28 | — | — | US | disclosed |
| EP-0223937-A1 | Indoles substituted with heterocycles, intermediates, process for their preparation and medicaments | Roche Diagnostics GmbH (DE) | 1987-06-03 | — | — | EP | disclosed |
| US-4587246-A | CARDIOTONIC | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-05-06 | — | — | US | disclosed |
| EP-0052442-B1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-09-11 | — | — | EP | disclosed |
| US-4503054-A | VASODILATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-05 | — | — | US | disclosed |
| US-4423045-A | CARDIOVASCULAR DISORDERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-12-27 | — | — | US | disclosed |
| EP-0052442-A1 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-05-26 | — | — | EP | disclosed |