⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15499258 | 0.82 | — | — | |
| SCHEMBL293592 | 0.81 | — | — | |
| SCHEMBL18886137 | 0.81 | — | — | |
| SCHEMBL28848000 | 0.78 | — | — | |
| SCHEMBL28444288 | 0.78 | MAPT (0.31) | — | |
| SCHEMBL5598602 | 0.78 | — | — | |
| SCHEMBL516849 | 0.77 | — | — | |
| SCHEMBL516848 | 0.77 | — | — | |
| SCHEMBL1005721 | 0.77 | — | — | |
| SCHEMBL21117056 | 0.77 | SLC6A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |