Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | MB | P02144 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845506 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL28867303 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL31202784 | 0.78 | POLB (0.51) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL31202582 | 0.77 | MAPT (0.57) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL31202719 | 0.77 | KMT2A (0.57) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL27254651 | 0.77 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10469562 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL31202780 | 0.76 | POLB (0.71) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL4579197 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8643836 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |