Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30293223 | 0.86 | HPGD (0.70) | HPGDPOLBMEN1KMT2AADRA2A | |
| SCHEMBL5213974 | 0.86 | HPGD (0.70) | HPGDPOLBMEN1KMT2AADRA2A | |
| SCHEMBL27296976 | 0.85 | HPGD (0.74) | HPGDMEN1KMT2AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL30293267 | 0.84 | HPGD (0.68) | HPGDPOLBMEN1KMT2AADRA2A | |
| SCHEMBL5215688 | 0.83 | HPGD (0.53) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL11692973 | 0.83 | KMT2A (0.56) | HPGDPOLBMEN1KMT2AHSD17B3 | |
| SCHEMBL13167920 | 0.83 | HPGD (0.53) | HPGDPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6140745 | 0.80 | CA12 (0.59) | POLBMEN1KMT2ACA12CA1 | |
| SCHEMBL11696347 | 0.80 | POLB (0.68) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL7287582 | 0.80 | CA12 (0.68) | HPGDPOLBMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036394-C | Process for preparing quinolone derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-11-12 | — | — | CN | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| US-5356904-A | Administering to prevent preterm labor in mammals | MERCK & CO., INC. (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |