Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27239639 | 0.86 | — | — | |
| SCHEMBL21177835 | 0.82 | MEN1 (0.32) | KMT2A | |
| SCHEMBL28662751 | 0.81 | KDM4E (0.36) | KDM4EKMT2A | |
| Ethinamate SCHEMBL44635 | 0.80 | MEN1 (0.34) | KMT2A | |
| SCHEMBL25475344 | 0.77 | — | — | |
| SCHEMBL27496881 | 0.77 | KDM4E (0.30) | KDM4EKMT2A | |
| SCHEMBL26785451 | 0.75 | — | — | |
| SCHEMBL25475260 | 0.74 | — | — | |
| SCHEMBL25475370 | 0.74 | — | — | |
| SCHEMBL26784749 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028531-C | 1-oxa-2-oxo-8-azaspiro [4,5] decane derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZET (HU) | 1995-05-24 | — | — | CN | claimed |
| EP-0414422-B1 | 2-Oxo-1-oxa-8-azaspiro [4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1994-04-06 | — | — | EP | claimed |
| EP-0414421-B1 | 1-Oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1994-04-06 | — | — | EP | claimed |
| EP-0412820-B1 | 2-Oxo-1-oxa-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1994-03-02 | — | — | EP | claimed |
| EP-0414421-A2 | 1-Oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-27 | — | — | EP | claimed |
| EP-0414422-A2 | 2-Oxo-1-oxa-8-azaspiro [4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-27 | — | — | EP | claimed |
| EP-0412820-A2 | 2-Oxo-1-oxa-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-13 | — | — | EP | claimed |
| JP-3077886-A | — | — | None | — | — | JP | disclosed |
| CN-1029403-C | 2-oxo-1-oxa-8-azaspiro [4,5] decane derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZET (HU) | 1995-08-02 | — | — | CN | disclosed |
| CN-1028531-C | 1-oxa-2-oxo-8-azaspiro [4,5] decane derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZET (HU) | 1995-05-24 | — | — | CN | disclosed |
| EP-0412821-B1 | 1-oxa-2-oxo-3,8-diazaspiro[4,5]decane derivatives, pharmaceutical compositions containing them and processes for preparing them | RICHTER GEDEON VEGYESZET (HU) | 1994-11-09 | — | — | EP | disclosed |
| EP-0413516-B1 | 4-Methylene-1-oxa-2-oxo-8-azaspiro[4,5]decane derivatives, pharmaceutical compositions containing them and processes for preparing them | RICHTER GEDEON VEGYESZET (HU) | 1994-04-20 | — | — | EP | disclosed |
| EP-0414421-B1 | 1-Oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1994-04-06 | — | — | EP | disclosed |
| JP-H0377886-A | NEW 2-OXO-1-OXA-8-AZASPIRO(4,5)DECANE DERIVATIVE, MEDICINE INCLUDING THE SAME, AND PREPARATION OF THE SAME | RICHTER GEDEON V G RT | 1991-04-03 | — | — | JP | disclosed |
| EP-0414421-A2 | 1-Oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-27 | — | — | EP | disclosed |
| EP-0414422-A2 | 2-Oxo-1-oxa-8-azaspiro [4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-27 | — | — | EP | disclosed |
| EP-0413516-A2 | 4-Methylene-1-oxa-2-oxo-8-azaspiro[4,5]decane derivatives, pharmaceutical compositions containing them and processes for preparing them | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-20 | — | — | EP | disclosed |
| CN-1049348-A | New 2-oxo-1-oxa--8-azaspiro [4,5] decane derivative contains their pharmaceutical composition and preparation method thereof | RICHTER GEDEON VEGYESZET (HU) | 1991-02-20 | — | — | CN | disclosed |
| EP-0412821-A2 | 1-oxa-2-oxo-3,8-diazaspiro[4,5]decane derivatives, pharmaceutical compositions containing them and processes for preparing them | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-13 | — | — | EP | disclosed |
| EP-0412820-A2 | 2-Oxo-1-oxa-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-13 | — | — | EP | disclosed |