Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.68 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496350 | 0.90 | F2 (0.57) | F2FKBP1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4695244 | 0.90 | F2 (0.57) | F2FKBP1AALDH1A1CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL495561 | 0.89 | F2 (0.59) | F2FKBP1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7292641 | 0.87 | F2 (0.53) | F2FKBP1AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4696097 | 0.86 | ACE (0.51) | F2CYP2C19 | |
| SCHEMBL15062947 | 0.86 | ACE (0.51) | F2CYP2C19 | |
| SCHEMBL8241847 | 0.86 | F2 (0.52) | F2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL495815 | 0.85 | F2 (0.52) | F2POLB | |
| Hydrochloric Acid SCHEMBL495585 | 0.85 | F2 (0.54) | F2ALDH1A1CYP3A4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL495583 | 0.85 | F2 (0.54) | F2ALDH1A1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346847-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 1994-05-11 | — | — | EP | disclosed |