Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330458 | 0.89 | TSHR (0.68) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| SCHEMBL21059490 | 0.89 | TSHR (0.68) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| SCHEMBL17040592 | 0.87 | TSHR (0.53) | TSHRHTR2AHTR2CHTR2BGAA | |
| SCHEMBL21059459 | 0.85 | TSHR (0.62) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| SCHEMBL21059457 | 0.85 | TSHR (0.62) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| SCHEMBL2111486 | 0.84 | TSHR (0.69) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| SCHEMBL21057148 | 0.84 | TSHR (0.69) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| SCHEMBL14419369 | 0.84 | TSHR (0.61) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| Rac-Dichlorprop SCHEMBL54510 | 0.83 | TSHR (0.73) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| (S)-Dichlorprop SCHEMBL1535831 | 0.83 | TSHR (0.73) | TSHRHTR2AHTR2CHTR2BPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |