Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439903 | 1.00 | KMT2A (0.33) | KMT2ABCHESPHK1CTSSCTSK | |
| SCHEMBL7439907 | 1.00 | KMT2A (0.33) | KMT2ABCHESPHK1CTSSCTSK | |
| SCHEMBL7439912 | 1.00 | KMT2A (0.33) | KMT2ABCHESPHK1CTSSCTSK | |
| SCHEMBL7295750 | 0.92 | KMT2A (0.30) | KMT2A | |
| SCHEMBL10531006 | 0.90 | EPHX1 (0.33) | KMT2ASPHK1CTSSCTSKBACE1 | |
| SCHEMBL9556570 | 0.88 | BACE1 (0.33) | KMT2ASPHK1CTSSCTSKBACE1 | |
| SCHEMBL7362140 | 0.88 | SPHK1 (0.31) | SPHK1CTSSCTSKBACE1CTSD | |
| SCHEMBL9556792 | 0.85 | SPHK1 (0.31) | SPHK1CTSSCTSKBACE1CTSD | |
| SCHEMBL9506660 | 0.84 | BACE1 (0.33) | SPHK1CTSSCTSKBACE1CTSD | |
| SCHEMBL9556483 | 0.84 | BACE1 (0.33) | SPHK1CTSSCTSKBACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397779-A1 | RENIN INHIBITING PEPTIDES WITH POLAR END GROUPS | THE UPJOHN COMPANY (US) | 1990-11-22 | — | — | EP | disclosed |
| WO-1990002137-A1 | RENIN INHIBITORY PEPTIDES CONTAINING SULEPTANIC ACID OR DERIVATIVES THEREOF | THE UPJOHN COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |
| EP-0355065-A1 | Renin inhibitory peptides containing suleptanic acid or derivatives thereof | THE UPJOHN COMPANY (US) | 1990-02-21 | — | — | EP | disclosed |
| EP-0329295-A1 | Renin inhibiting peptides with polar end groups | THE UPJOHN COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |
| WO-1989007109-A1 | RENIN INHIBITING PEPTIDES WITH POLAR END GROUPS | THE UPJOHN COMPANY (US) | 1989-08-10 | — | — | WO | disclosed |