SCHEMBL7293429

SCHEMBL7293429

NC(CCC(=O)NC(Cc1ccc(O)c(O)c1)C(=O)O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 4/20 0.62
▸ LCK P06239 2/20 0.62
▸ PTGS1 P23219 2/20 0.62
▸ KDM4E B2RXH2 1/20 0.62
▸ USP2 O75604 1/20 0.62
▸ EGFR P00533 1/20 0.62
▸ FYN P06241 1/20 0.62
▸ ADORA3 P0DMS8 1/20 0.62
▸ ALOX15 P16050 1/20 0.62
▸ HTR2A P28223 1/20 0.62
▸ PTGS2 P35354 1/20 0.62
▸ RECQL P46063 1/20 0.62
▸ HIF1A Q16665 1/20 0.62
▸ HSD17B10 Q99714 1/20 0.62
▸ TDP1 Q9NUW8 1/20 0.62
▸ CA1 P00915 3/20 0.55
▸ CA2 P00918 3/20 0.55
▸ FOLH1 Q04609 3/20 0.53
▸ MME P08473 1/20 0.50
▸ ACE P12821 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27753212 1.00 SLC7A5 (0.62) SLC7A5LCKPTGS1KDM4EUSP2
SCHEMBL11576781 1.00 SLC7A5 (0.62) SLC7A5LCKPTGS1KDM4EUSP2
SCHEMBL29711137 1.00 SLC7A5 (0.62) SLC7A5LCKPTGS1KDM4EUSP2
SCHEMBL7293361 0.87 SLC7A5 (0.53) SLC7A5LCKPTGS1KDM4EUSP2
SCHEMBL159886 0.86 NAALAD2 (0.59) SLC7A5CA1CA2FOLH1MME
SCHEMBL159887 0.86 NAALAD2 (0.59) SLC7A5CA1CA2FOLH1MME
SCHEMBL2339748 0.85 CA1 (0.58) SLC7A5LCKPTGS1KDM4EUSP2
SCHEMBL2339741 0.85 CA1 (0.58) SLC7A5LCKPTGS1KDM4EUSP2
SCHEMBL28711871 0.85 FOLH1 (0.57) SLC7A5LCKPTGS1KDM4EUSP2
SCHEMBL9628000 0.83 ACE (0.58) SLC7A5PTGS1MMEACENAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61063296-A — — None — — JP disclosed
JP-6225761-A — — None — — JP disclosed
CN-115838678-B Secretion expression glutaminase strain, construction method and application thereof 安琪酵母股份有限公司 2025-05-27 — — CN disclosed
CN-117417953-A Construct and secretory expression gamma-glutamyl transpeptidase strain 安琪酵母股份有限公司 2024-01-19 — — CN disclosed
CN-115838678-A Strain for secretory expression of glutaminase and construction method and application thereof 安琪酵母股份有限公司 2023-03-24 — — CN disclosed
JP-H06225761-A NEW MUTANT GAMMA-GLUTAMYL TRANSPEPTIDASE FUJISAWA PHARMACEUT CO LTD 1994-08-16 — — JP disclosed
EP-0352815-B1 PRODRUGS OF DOPAMINE ZAMBON GROUP S.p.A. (IT) 1993-05-19 — — EP disclosed
US-5013753-A Prodrugs of dopamine SIMES (IT) 1991-05-07 — — US disclosed
EP-0352815-A1 Prodrugs of dopamine ZAMBON GROUP S.p.A. (IT) 1990-01-31 — — EP disclosed
JP-S6163296-A PRODUCTION OF GAMMA-GLUTAMYLDOPA AND GAMMA-GLUTAMYLDOPA DERIVATIVE AJINOMOTO CO INC 1986-04-01 — — JP disclosed
JP-S06163296-A — — 0001-01-01 — — JP disclosed
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