Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567744 | 1.00 | POLB (0.56) | POLBCNR2MEN1CYP1A2KMT2A | |
| SCHEMBL6439569 | 1.00 | POLB (0.56) | POLBCNR2MEN1CYP1A2KMT2A | |
| Sulfurous Acid SCHEMBL5567229 | 0.94 | CNR2 (0.54) | POLBCNR2MEN1CYP1A2KMT2A | |
| Sulfurous Acid SCHEMBL28752565 | 0.94 | CNR2 (0.54) | POLBCNR2MEN1CYP1A2KMT2A | |
| SCHEMBL7300117 | 0.84 | HDAC2 (0.51) | CNR2MEN1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL3024846 | 0.83 | POLB (0.59) | POLBCNR2MEN1CYP1A2KMT2A | |
| SCHEMBL3024849 | 0.83 | POLB (0.59) | POLBCNR2MEN1CYP1A2KMT2A | |
| SCHEMBL19099236 | 0.80 | POLB (0.63) | POLBCNR2MEN1CYP1A2KMT2A | |
| SCHEMBL14701618 | 0.80 | POLB (0.63) | POLBCNR2MEN1CYP1A2KMT2A | |
| SCHEMBL7674546 | 0.79 | POLB (0.67) | POLBCNR2MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008228-A | COMPRISING A MIXTURE OF CARRIER MONOGLYCERIDES OF MEDIUM CHAIN-FATTY ACIDS | HOFFMAN-LA ROCHE INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0594540-B1 | Antiretroviral acyl compounds | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| CN-1089606-A | Antiretroviral acyl compounds | CIBA GEIGY AG (CH) | 1994-07-20 | — | — | CN | disclosed |
| EP-0594540-A1 | Antiretroviral acyl compounds | CIBA-GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |