Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.40 |
| ▸ | NOS2 | P35228 | 5/20 | 0.40 |
| ▸ | NOS1 | P29475 | 4/20 | 0.40 |
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036485 | 0.79 | GSR (0.52) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL13084137 | 0.78 | GSR (0.59) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL14215018 | 0.78 | GSR (0.59) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL27429278 | 0.78 | GSR (0.59) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL13592271 | 0.78 | GSR (0.59) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL12277980 | 0.77 | GSR (0.64) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL2043064 | 0.77 | GSR (0.64) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL2603680 | 0.77 | GSR (0.64) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL17365415 | 0.77 | GSR (0.53) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL19816440 | 0.75 | GSR (0.61) | GSRGNAI3GNAO1GNAI1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343911-A2 | Cycloalkyl-substituted glutaramide diuretic agents | Pfizer Limited (GB) | 1989-11-29 | — | — | EP | claimed |