⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31120428 | 0.71 | — | — | |
| SCHEMBL14678811 | 0.67 | — | — | |
| SCHEMBL3817396 | 0.65 | — | — | |
| SCHEMBL6278270 | 0.63 | — | — | |
| SCHEMBL16167605 | 0.63 | — | — | |
| SCHEMBL13271065 | 0.62 | — | — | |
| SCHEMBL824206 | 0.62 | — | — | |
| SCHEMBL4743726 | 0.62 | — | — | |
| SCHEMBL18587945 | 0.62 | — | — | |
| SCHEMBL17082629 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353712-A1 | METHODS OF DIAGNOSING AND TREATING VASCULAR ASSOCIATED MACULOPATHY AND SYMPTOMS THEREOF | UNIV UTAH RES FOUND (US) | 2021-11-18 | — | — | US | claimed |
| EP-2686007-B1 | METHODS OF DIAGNOSING AND TREATING VASCULAR ASSOCIATED MACULOPATHY AND SYMPTOMS THEREOF | UNIV UTAH RES FOUND (US) | 2019-04-24 | — | — | EP | claimed |
| CN-103841991-B | Diagnosis and the method for the treatment of blood vessel related maculopathy and its symptom | 犹他大学研究基金会 | 2018-03-27 | — | — | CN | claimed |
| US-20140323413-A1 | METHODS OF DIAGNOSING AND TREATING VASCULAR ASSOCIATED MACULOPATHY AND SYMPTOMS THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2014-10-30 | — | — | US | claimed |
| EP-2686007-A2 | METHODS OF DIAGNOSING AND TREATING VASCULAR ASSOCIATED MACULOPATHY AND SYMPTOMS THEREOF | University of Utah Research Foundation (US) | 2014-01-22 | — | — | EP | claimed |
| WO-2012125872-A2 | METHODS OF DIAGNOSING AND TREATING VASCULAR ASSOCIATED MACULOPATHY AND SYMPTOMS THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-09-20 | — | — | WO | claimed |
| EP-0591773-A1 | 3-imino-3-alkoxy-propionicacidlactates and the tautomer acroylicacidlactates | BAYER AG (DE) | 1994-04-13 | — | — | EP | claimed |
| EP-0179386-B1 | 1,4-DIHYDROPYRIDINE HYDROXYAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL AGENTS | BAYER AG (DE) | 1989-06-07 | — | — | EP | claimed |
| CN-85107866-A | 1,4-dihydropyridine-oxyamine, their preparation method and in pharmaceutically application | — | 1986-07-30 | — | — | CN | claimed |
| EP-0179386-A2 | 1,4-Dihydropyridine hydroxyamines, process for their preparation and their use as pharmaceutical agents | BAYER AG (DE) | 1986-04-30 | — | — | EP | claimed |
| JP-6220001-A | — | — | None | — | — | JP | disclosed |
| CN-114907354-B | Sulfonamide polycyclic compound and preparation method and application thereof | 南京知和医药科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-20230233645-A1 | EFFECTIVE TREATMENTS FOR VASCULAR ASSOCIATED MACULOPATHY, SEVERE MACULOPATHY, LATE-STAGE MACULOPATHY, AND ABERRANT CHORIOCAPILLARIS | UNIV UTAH RES FOUND (US) | 2023-07-27 | — | — | US | disclosed |
| CN-115894587-A | Preparation of nucleoside derivative and application of nucleoside derivative in field of antiviral drugs | 知和(山东)大药厂有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114907354-A | Sulfonamide polycyclic compound and preparation method and application thereof | 南京知和医药科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| US-4698341-A | Use of 1,6-naphthyridinone derivatives in treating pulmonary thrombosis | GODECKE AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | disclosed |
| EP-0189898-A1 | 1,6-Nephthyridinone derivatives and process for their preparation | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1986-08-06 | — | — | EP | disclosed |
| CN-85107866-A | 1,4-dihydropyridine-oxyamine, their preparation method and in pharmaceutically application | — | 1986-07-30 | — | — | CN | disclosed |
| EP-0179386-A2 | 1,4-Dihydropyridine hydroxyamines, process for their preparation and their use as pharmaceutical agents | BAYER AG (DE) | 1986-04-30 | — | — | EP | disclosed |
| US-4500528-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |