SCHEMBL7295002

SCHEMBL7295002

CCOC(=O)C1CCCCN1C(=O)CC1CCc2ccccc2C1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PREP P48147 17/20 0.66
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
FKBP1A P62942 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7299524 0.97 PREP (0.67) PREPALDH1A1
SCHEMBL7295390 0.94 PREP (0.64) PREPKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL7296815 0.85 PREP (0.70) PREP
SCHEMBL7294917 0.85 PREP (0.70) PREP
SCHEMBL7292882 0.85 PREP (0.70) PREP
SCHEMBL7294906 0.85 PREP (0.70) PREP
SCHEMBL7294112 0.84 PREP (0.74) PREP
SCHEMBL7304041 0.82 PREP (0.51) PREPKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL7295161 0.82 PREP (0.95) PREP
SCHEMBL7294701 0.82 PREP (0.95) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed