SCHEMBL7296133

SCHEMBL7296133

CN(C)CCCCn1nc(-c2c(-c3ccccc3)nn3ccccc23)ccc1=O

nearest known ligand 0.73

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.73
IGF1R P08069 1/20 0.46
MAPK1 P28482 4/20 0.43
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7296302 0.99 ADORA1 (0.71) ADORA1IGF1RMAPK1USP2
Hydrochloric Acid SCHEMBL7291661 0.96 ADORA1 (0.73) ADORA1IGF1RMAPK1USP2
Hydrochloric Acid SCHEMBL7301696 0.93 ADORA1 (0.68) ADORA1IGF1RMAPK1USP2
SCHEMBL7294123 0.87 ADORA1 (0.79) ADORA1IGF1RMAPK1
SCHEMBL7303206 0.86 ADORA1 (0.74) ADORA1IGF1RMAPK1
SCHEMBL7290705 0.86 ADORA1 (0.74) ADORA1IGF1RMAPK1
SCHEMBL7301601 0.86 ADORA1 (0.74) ADORA1IGF1RMAPK1
SCHEMBL7295163 0.86 ADORA1 (0.74) ADORA1IGF1RMAPK1
SCHEMBL7299845 0.86 ADORA1 (0.74) ADORA1IGF1RMAPK1
SCHEMBL7295140 0.86 ADORA1 (0.74) ADORA1IGF1RMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0497258-B1 Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer FUJISAWA PHARMACEUTICAL CO (JP) 2002-01-02 EP disclosed
EP-0467248-B1 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1998-10-28 EP disclosed
US-5338743-A Pancreatitis FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-08-16 US disclosed
US-5204346-A Cognition activators; analgesics; antidepressants; vasodilation; cardiovascular and urogential disorders; FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-04-20 US disclosed
EP-0497258-A2 Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-08-05 EP disclosed
EP-0467248-A2 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-01-22 EP disclosed