SCHEMBL7296164

SCHEMBL7296164

O=C([C@@H]1CCCN1C(=O)C1CCc2ccccc2C1)N1CCSC1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PREP P48147 16/20 0.70
F2 P00734 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7296166 1.00 PREP (0.70) PREPF2
SCHEMBL7294137 0.97 PREP (0.66) PREPF2
SCHEMBL7292814 0.86 PREP (0.67) PREPF2
SCHEMBL7292823 0.86 PREP (0.67) PREPF2
SCHEMBL7300952 0.83 PREP (0.63) PREPF2
SCHEMBL7295630 0.83 F2 (0.60) PREPF2
SCHEMBL7301727 0.83 PREP (1.00) PREP
SCHEMBL8152338 0.83 PREP (1.00) PREP
SCHEMBL8155762 0.83 PREP (1.00) PREP
SCHEMBL7294646 0.83 PREP (1.00) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017929-A Cholinesterase activator ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-01-25 US disclosed
EP-0754454-A1 CHOLINESTERASE ACTIVATOR ZERIA PHARMACEUTICAL CO., LTD. (JP) 1997-01-22 EP disclosed
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed