⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hypochlorous Acid SCHEMBL8434801 | 1.00 | — | — | |
| Hypochlorous Acid SCHEMBL27541286 | 0.87 | TSHR (0.60) | — | |
| SCHEMBL30922366 | 0.87 | — | — | |
| SCHEMBL143391 | 0.87 | — | — | |
| Hypochlorous Acid SCHEMBL15644 | 0.87 | — | — | |
| Hypochlorous Acid SCHEMBL811532 | 0.87 | — | — | |
| Hypochlorous Acid SCHEMBL28907544 | 0.87 | TSHR (0.60) | — | |
| Hypochlorous Acid SCHEMBL482943 | 0.87 | — | — | |
| Carbon Tetrachloride SCHEMBL10754436 | 0.82 | — | — | |
| Hypochlorous Acid SCHEMBL23236460 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009157014-A2 | A PROCESS FOR PREPARING HMG-COA REDUCTASE INHIBITORS AND INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2009-12-30 | — | — | WO | claimed |
| EP-0538384-A4 | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | claimed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | claimed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | claimed |
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| EP-2403846-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2016-11-02 | — | — | EP | disclosed |
| CN-105001206-A | Inhibitors of Bruton's Tyrosine Kinase | HOFFMANN LA ROCHE | 2015-10-28 | — | — | CN | disclosed |
| CN-102341383-B | Inhibitors of bruton's tyrosine kinase | HOFFMAN-LA ROCHE LTD. (CH) | 2015-09-16 | — | — | CN | disclosed |
| EP-2307413-B1 | NOVEL PHENYL-IMIDAZOPYRIDINES AND PYRIDAZINES | HOFFMANN LA ROCHE (CH) | 2015-09-09 | — | — | EP | disclosed |
| US-8883833-B2 | Substituted benzoazole PDE4 inhibitors for treating inflammatory, cardiovascular and CNS disorders | DECODE GENETICS EHF (IS) | 2014-11-11 | — | — | US | disclosed |
| US-8785657-B2 | Processes for the preparation of pyrazoles | SYNGENTA CROP PROTECTION LLC (US) | 2014-07-22 | — | — | US | disclosed |
| US-8536166-B2 | Inhibitors of Burton's tyrosine kinase | ROCHE PALO ALTO LLC (US) | 2013-09-17 | — | — | US | disclosed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0533439-A2 | Constant-voltage diode, power converter using the same and process of producing constant-voltage diode | HITACHI, LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |
| EP-0174761-B1 | P-FORMYL-N,N-DIPOLYOXYALKYLENE-SUBSTITUTED ANILINES AND THEIR PREPARATION | MILLIKEN RESEARCH CORPORATION (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4654338-A | TREATING ANXIETY IN WARM BLOODED ANIMALS | ROUSSEL ULCAF (FR) | 1987-03-31 | — | — | US | disclosed |
| US-4173679-A | A REACTION PRODUCT OF POLYPHOSPHORIC ACID AND AN ETHOXYLATED CARBOXYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |
| US-4161486-A | Cleavage of silicon-to-carbon bonds by means of hydrogen halide | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |
| US-3980574-A | Lubricant containing diorganophosphorus derivatives of urethane as antiwear agents | MOBIL OIL CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |