Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.63 |
| ▸ | ANPEP | P15144 | 1/20 | 0.61 |
| ▸ | DPP4 | P27487 | 2/20 | 0.59 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31134030 | 0.93 | DPP8 (0.68) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL16476534 | 0.89 | DPP8 (0.67) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL10821457 | 0.89 | DPP8 (0.67) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL6356988 | 0.89 | DPP8 (0.67) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL4363399 | 0.89 | DPP8 (0.67) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL12131715 | 0.89 | DPP8 (0.67) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL3704 | 0.89 | DPP8 (0.69) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL3703 | 0.89 | DPP8 (0.69) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL10962932 | 0.89 | DPP8 (0.69) | DPP8DPP7ANPEPDPP4DPP9 | |
| Hydrochloric Acid SCHEMBL5189156 | 0.88 | DPP8 (0.65) | DPP8DPP7ANPEPDPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343911-A2 | Cycloalkyl-substituted glutaramide diuretic agents | Pfizer Limited (GB) | 1989-11-29 | — | — | EP | disclosed |