Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443040 | 0.85 | CTNNB1 (0.43) | CTNNB1CTSSCTSKKMT2ATDP1 | |
| SCHEMBL8484930 | 0.83 | CTNNB1 (0.51) | CTNNB1KMT2ATDP1CYP1A2CYP2C19 | |
| SCHEMBL7271887 | 0.82 | KMT2A (0.54) | CTNNB1KMT2ATDP1CYP1A2CYP2C19 | |
| SCHEMBL6447751 | 0.78 | CTNNB1 (0.42) | CTNNB1CTSSCTSKKMT2ATDP1 | |
| SCHEMBL6447142 | 0.78 | CTNNB1 (0.41) | CTNNB1CTSSCTSKKMT2ATDP1 | |
| SCHEMBL10389712 | 0.76 | CTNNB1 (0.50) | CTNNB1CTSSCTSKKMT2ATDP1 | |
| SCHEMBL6445965 | 0.76 | CTNNB1 (0.45) | CTNNB1CTSSCTSKTDP1CYP1A2 | |
| SCHEMBL7302653 | 0.75 | HTR1B (0.43) | CTNNB1CYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL11214375 | 0.75 | ATM (0.50) | TDP1CYP1A2CYP2C19CYP2C9SIGMAR1 | |
| SCHEMBL31258909 | 0.75 | ATM (0.50) | TDP1CYP1A2CYP2C19CYP2C9SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594540-A1 | Antiretroviral acyl compounds | CIBA-GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |