Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GLB1 | P16278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886944 | 1.00 | GBA1 (0.31) | GBA1SIPYGLGBA2GAA | |
| SCHEMBL12559865 | 1.00 | GBA1 (0.31) | GBA1SIPYGLGBA2GAA | |
| SCHEMBL9310298 | 1.00 | GBA1 (0.31) | GBA1SIPYGLGBA2GAA | |
| SCHEMBL1707289 | 1.00 | GBA1 (0.31) | GBA1SIPYGLGBA2GAA | |
| SCHEMBL9685994 | 0.86 | FUCA1 (0.30) | — | |
| SCHEMBL9517983 | 0.82 | — | — | |
| SCHEMBL9517203 | 0.82 | — | — | |
| SCHEMBL9593313 | 0.82 | — | — | |
| SCHEMBL25393489 | 0.80 | — | — | |
| SCHEMBL2030916 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011162562-A2 | [6+5] FUSED BICYCLES AS A THROMBIN ANTAGONIST, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE BICYCLES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011162562-A2 | [6+5] FUSED BICYCLES AS A THROMBIN ANTAGONIST, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE BICYCLES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-12-29 | — | — | WO | disclosed |
| US-5583248-A | Amino acid derivatives having antiviral activity | HOFFMANN-LA ROCHE INC. (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0512343-B1 | Amino acid derivatives and their use as anti-viral agents | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | EP | disclosed |
| US-5430041-A | Amino acid derivatives having antiviral activity | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0399633-B1 | Leukotriene B4 derivatives, process for their preparation and their use as medicines | SCHERING AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| US-5239118-A | Cyclic conjugated enediynes | TRUSTEES OF THE UNIVERSITY OF PENNA. (US) | 1993-08-24 | — | — | US | disclosed |
| US-5187286-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| EP-0512343-A2 | Amino acid derivatives and their use as anti-viral agents | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5097062-A | Cyclic conjugated enediynes | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 1992-03-17 | — | — | US | disclosed |