SCHEMBL7297328

SCHEMBL7297328

O=C(CC1CCc2ccccc2C1)C1C(=S)CN[C@@H]1C(=O)N1CCC[C@H]1CO

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PREP P48147 16/20 0.46
CHRM2 P08172 3/20 0.39
CHRM4 P08173 3/20 0.39
CHRM1 P11229 3/20 0.39
CHRM3 P20309 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8161220 1.00 PREP (0.46) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL9047373 1.00 PREP (0.46) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL8161139 0.95 PREP (0.43) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL9050170 0.91 PREP (0.40) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL9049419 0.89 PREP (0.39) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL9049657 0.89 PREP (0.39) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL9049004 0.89 GBA1 (0.40) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL9171673 0.89 GBA1 (0.40) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL9048719 0.88 PREP (0.46) PREP
SCHEMBL8146773 0.88 PREP (0.46) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed