Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332466 | 0.76 | CHRM1 (0.33) | POLBCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4338602 | 0.75 | TSHR (0.32) | TSHRFDPS | |
| SCHEMBL4338605 | 0.75 | TSHR (0.32) | TSHRFDPS | |
| SCHEMBL8249566 | 0.72 | CHRM1 (0.40) | POLBCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL26052114 | 0.70 | — | — | |
| SCHEMBL29018970 | 0.70 | CHRM1 (0.39) | POLBCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9768619 | 0.69 | TP53 (0.31) | — | |
| SCHEMBL9768623 | 0.69 | TP53 (0.31) | — | |
| SCHEMBL1056648 | 0.69 | — | — | |
| SCHEMBL15386600 | 0.68 | CA1 (0.45) | TSHRCA1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000846-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2012-01-05 | — | — | WO | disclosed |